Download Advances in Critical Care Testing: The 2002 IFCC-Roche by S. Zeerleder, B. Zwart, W. A. Wuillemin, L. A. Aarden, A. B. PDF

By S. Zeerleder, B. Zwart, W. A. Wuillemin, L. A. Aarden, A. B. J. Groeneveld, C. Caliez (auth.), Carl A. Burtis, Mathias M. Müller (eds.)

Advances in severe Care Testing includes scientific and laboratory reviews regarding severely in poor health sufferers concerning new expertise, treatment, and alertness or interpretation of latest checks. the subject material of the e-book is of curiosity to either clinicians and laboratory scientists with a variety of themes together with irritation, an infection, rigidity, hypoxia, ischaemia, cardiology, haemodynamics, blood gases, electrolytes, hint components, nephrology, gastroenterology, haematology and new applied sciences.

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Additional info for Advances in Critical Care Testing: The 2002 IFCC-Roche Diagnostics Award

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0\0). 0\2. S = survivors, NS = non- urvivors a b 26 R. ver Elst, L. Huyghens, F. Gorus Table 5. Changes in C-reactive protein (CRP) concentrations at various time points versus baseline in 53 patients with acute septic shock" Patients followed over 24 hours Survivors Non-survivors P CRP at admission; mg/I. 215 change in CRP vs baseline; mg/I. 134 CRP at 120 hours; mg/I. 011 CPR at 48 hours; mg/I. (n =47: 26 S, 23 NS)b change in CRP vs baseline; mg/I. change in CRP vs baseline; % • all results are median (interquartile range); p-values are calculated by Mann-Whitney U test b missing data are due to insufficient serum sample or death of patients within 24,48 or 120 hours after onset of septic shock.

042) on admission, but no relation between TNF-a and MIF. IL-6 is a known activator of the HPA axis (36), but IL-6 is not known, in contrast to TNF-a or interferon-g, to induce MIF production (10). Apparently both severe trauma and septic shock are conditions leading to activation of the HPA axis with a paradoxically low ACTH level during prolonged illness. However,the changes in MIF concentrations were distinctive; the persistently elevated levels of MIF in septic shock contrasted with the normal levels in multiple trauma.

Blood was collected into plain tubes or into prechilled tubes containing ethylenediamine tetraacetate. Blood samples of the control subjects were collected by venipuncture between 0800-1000 h in the supine position after 30 min of rest. All hormone and cytokine measurements were performed in duplicate. , Kobe, Japan) parameters were assessed. Assays Immunoreactive cortisol, ACTH,tumor necrosis factor-a (TNF-a),and interleukin6 (lL-6) concentrations were measured with commercially available cherniluminescent enzyme immunoassays using the Immulite Automated Immunoassay System (Diagnostic Products, Los Angeles, CA).

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