Download Handbook of Listeria Monocytogenes by Dongyou Liu PDF

By Dongyou Liu

As soon as feared as a dangerous intracellular bacterium with the extreme capability to outlive a wide range of hard exterior stressors, Listeria monocytogenes is more and more famous as a popular vector for supplying anti-infective and anti-cancer vaccine molecules. a competent, single-source reference at the basic elements of this bacterium is important to aid destiny examine and extra the development of biomedical sciences and intervention options. Drawn from a world panel of scientists with striking services of their respective fields, the Handbook of Listeria monocytogenes is split into 4 sections: part I discusses the biology and pathogenicity of this bacterium, together with epidemiology and rigidity responses. part II demonstrates id and detection thoughts resembling phenotypic and genotypic identity, pressure typing, and virulence choice. part III information the present wisdom of genetic manipulation of Listeria , together with comparative genomics, genomic divisions, epidemic clones and inhabitants constitution, and research of cellphone envelope proteins. part IV covers innate and adaptive immunity opposed to Listeria , and examines using this bacterium for anti-infective and anti-cancer vaccine improvement. the 1st accomplished compilation of information during this zone, this instruction manual is an vital reference for a person embarking at the direction of manipulation of Listeria as both a version for the learn of the host-bacterium dating or as a device for offering protecting molecules to cytoplasm.

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Extra info for Handbook of Listeria Monocytogenes

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A previous investigation showed that L. 44 A number of reports pointed out that pig tonsils (up to 61%) and tongues (up to 14%) were more likely to harbor L. 48 detected L. , tongue, esophagus, trachea, lungs, heart, diaphragm, kidneys, and liver), which might result from crosscontamination between tonsils/tongues and other viscera during processing. 47 found ground pork samples (45–50%) were more likely to contain L. monocytogenes than small intestines (8–9%). Although L. 27,50 Meat products have been associated with several notable listeriosis outbreaks worldwide.

Being free-living organisms, Listeria spp. have to endure various external stresses for their eventual survival in the environment. For example, in river water and sludge, Listeria spp. have to withstand near-freezing temperatures during winter and extreme outdoor heat in summer. In food processing environments, Listeria spp. are routinely exposed to alkaline detergents and sanitizers that are applied to clean and sterilize food-processing surfaces, machines, and floors. From the studies involving the pathogenic species L.

Interestingly, L. ivanovii was isolated only in the soil from animal-inhabited areas, but not in soil from agricultural fields. These findings highlight that Listeria spp. frequently occur in soil (with an average presence of 20%), where they probably live as saprophytes. 3 Plants and Vegetation In an early study, Welshimer21 isolated eight L. monocytogenes strains in vegetation collected from fields in Virginia. After examining vegetation or soil taken from 12 farms and seven nonagricultural sites, Welshimer and Donker-Voet22 also obtained 27 L.

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